Starting a Supplement Company – Part 2: Custom Formulating Dietary Supplements

If you recall our last post, we are sharing a new series of articles that will cover the variety of consulting services we are providing a new DSE client. They were telling us the target audience for their first product, giving us some steep specifications to meet, and requesting we handle many things from the formulation through the launch of the product.

The first step of the project was to come up with a few product formula concepts. In doing this, we followed our basic 8-step process for custom formulating dietary supplements that deliver on uniqueness, marketability, strong claims, and cost effectiveness:

Step 1: Concept Brief

In the concept brief stage, we listen to the client. Our goals here are to learn as much as we can about what the client wants. We are determining things like the product category, the target audience and sub-audiences, the desired claims to be made, dosage form, and budget limitations.

Step 2: Ingredient Surveying

This is where we really shine. With so many ingredient offerings out there, it is critical that formulators attend the trade shows, read the trade news, keep in touch with suppliers, watch the emerging science, and do everything they can to stay on top of what is hot and what has the scientific backing for claims. We like to pull together potential ingredients that are a balanced mix of hot studied and branded ingredients, classic well-studied ingredients, and some of those that might not have the strongest of science, but still may resonate in a formula because of trendiness or consumer expectations (e.g., raspberry ketones).

Step 3: Ingredient Screening

Once we have a pool of maybe 20 to 30 potential ingredients, we have to screen through them figure out which are most aligned with the goals established in Step 1. Reasons for elimination might be too high of cost for required dosage, low compatibility for the dosage form, not marketable enough, or perhaps just not right for the positioning. In most cases, 20 to 30 ingredients can be reduced to closer to 10.

Step 4: Concept Presentation

With 10 great ingredients, many different arrangements can be put together. Our usual approach, however, is to determine a few lead ingredients that we know can be dosed together in order to deliver the primary claims for the product. At least one of these we usually like to be something branded and/or novel. Two or three concepts are generally shown to the client for review. To present the concepts, we show the client Supplement Facts panels, along with bulleted lists of the anticipated structure/function claims that will be able to be made. At times, we can also at this point provide rough cost estimates for the concepts.

Step 5: Client Feedback

Rarely do the presented concepts immediately check all of the boxes for clients, but we usually arrive at the one or two concepts that are close. Here we listen again to the client to see what is working and what is not.

Step 6: Concept Refining

After we get the client feedback, we take the formula(s) back to the drawing board and make the refining adjustments needed to arrive at a final formula that addresses everything that came out of step 5. Here again we create a new Supplement Facts panel and bulleted set of anticipated claims.

Step 7: Concept Approval

We never want to create a custom formula that leaves the client unhappy. If we need to run through previous steps and go through many refinements, we will. However, the goal is to arrive at a concept approval stage. The client is content with everything presented to this point in the process.

Step 8: Purchasing Specifications

Having a custom formula selected is exciting for a client, but especially for those new to the supplement world, knowing how to make it a reality might be a little more daunting. We like to make things as easy as possible for our clients at this point. We create purchasing specifications that the client can provide to contract manufacturers (assuming the client isn’t going to be the manufacturer) to ensure that they are quoted for exactly the formulation needed.

For the new DSE client, we followed all of these eight steps to arrive at a custom formulation that the client loved. In this case, we started with about 20 ingredients, and narrowed them down to just two. Although a simple sounding formula, it included a very new and hot branded and studied ingredient, as well as another generic one with multiple clinical studies behind it. The ingredients delivered the desired claims perfectly, and the dosage form we came up with was something we have never done or even seen before. We are excited to share the details in a future post in this series.

If you have any questions about our custom formulation for dietary supplements services, please contact us to learn more.

Starting a Supplement Company – Part 1: Overview

Start Supplement Company

Recently, a new DSE client called up with a big, but typical consulting request. He was enthusiastic about a new project – ready to begin immediately. However, rather than having needs for just some of the typical items like label review, claims review, ingredient review, etc., the request this time was for everything, or at least virtually everything from product concept to product launch. This would be their first product for their new company.

If all of this weren’t enough, other than having a target market identified, the client also requested that the product concept we come up with be formulated with scientifically-studied ingredients with strong claims, contain at least one new and hot branded ingredient, have an eye-popping product name logo with out-of-the-box thinking design work, and if possible, be delivered in a form (e.g., not standard capsules or powder) rarely or never seen before. A very tall order.

In addition, the client of course wanted everything to be compliant for their new brand. Although he may not have known what exactly that would entail, we had to start thinking about label compliance, claims substantiation and submission to the FDA, sourcing cGMP-compliant manufacturing and conducting an audit, creating SOPs, lining up finished product testing, creating specifications for that, and more.

With a large task list, we began right away. Although many of the tasks were overlapping and varied in time to complete, in this series we will briefly describe how we took on this project, what was required, and what the outcomes were. The client requested that we not reveal too many details of the actual product prior to their launch, but we will be excited to show what we come up with in the end.

The following are some of the tasks we will cover in this series:

  • Determining market needs and desired product claims
  • Ingredient screening
  • Proposing multiple formulations to fit market needs and desired product claims, as well as budget
  • Requesting multiple quotes
  • Selecting a manufacturer and auditing
  • Creating product specifications
  • Logo and compliant label design
  • Structure/function claims drafting, substantiating, and submitting
  • Creating a set of SOPs
  • Creating advertising copy
  • Facilitating finished product testing
  • And likely more

We hope you will enjoy this series of articles. You will get a glimpse into how we assist clients, and maybe find something you can apply to your business.